Zepbound
Zepbound is the brand name for tirzepatide approved for weight loss. It's the same active ingredient as Mounjaro (approved for diabetes) but marketed specifically for obesity treatment.
Brand-Name Cost
$1,000-1,200/month
Compounded Cost
N/A (brand only)
Type
GLP-1/GIP Agonist
How Zepbound Works
Zepbound is a dual-action medication that activates both GIP and GLP-1 receptors. This unique mechanism reduces appetite, slows digestion, and improves how your body handles blood sugar and fat.
Effectiveness
SURMOUNT trials showed average weight loss of 20-22% of body weight. In head-to-head trials, tirzepatide showed greater weight loss than semaglutide (20.2% vs 13.7%).
Dosing
Weekly injection with dose escalation: 2.5mg (weeks 1-4), 5mg (weeks 5-8), then increasing to 10mg or 15mg based on response. Some patients do well on lower maintenance doses.
FDA-Approved Uses
- Chronic weight management in adults with obesity or overweight with weight-related conditions
Get GLP-1 Updates
Weekly pricing updates, FDA news, and new provider reviews delivered to your inbox.